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Approximately 20% of patients with primary ovarian insufficiency (POI) have been diagnosed with other autoimmune diseases, often thyroid, adrenal, and pancreatic diseases, and approximately 10% of patients with Addisons disease develop POI ( Figure 2 2.1.3 Iatrogenic factors Chemotherapy has multiple effects on ovarian function ( 2.1.4 Metabolic factors Ovarian function is decreased in patients with galactosemia, but the mechanisms responsible for this remain unclear

Lin H, Chen Y, Shi J

Moakes, R

Numbers reflect published research, manufacturer/pharmacy ranges, and community-derived planning patterns

Bu tanmlama, aratrma kimyasallarnn yalnzca vitro testler ve laboratuvar deneyleri iin kullanlmasna izin verir

Some preclinical work explores FOXO4-p53-targeting peptides against senescent cancer cells, and the developer has discussed cancer as a research interest, but there is no human evidence that FOXO4-DRI treats cancer