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POF, Premature Ovarian Failure

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doi:10.1111/bdi.13039

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Nitric oxide (NO) signaling cascade The generation of nitric oxide (NO) catalyzed by endothelial nitric oxide synthase (eNOS) plays a critical role in protecting the vascular endothelium from oxidative and inflammatory insults (27)

doi: 10.1016/0006-291X(85)91669-9