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Description

Averaged spectra were analyzed using LCModel v.6.31N 69

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Tischer, A., Moon-Tasson, L

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Blood 106:942a, 2006

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The functional antagonism between Th17 cells and Treg cells primarily manifests in their reciprocal interactions and regulatory mechanisms within the immune system ( Treg cells mainly fall into four categories and use direct or indirect interaction to carry out immunosuppressive actions: 1) Cytokine-mediated suppression: TGF-, IL-10, and IL-35 induce Treg development, prevent antigen-presenting cell (APC) maturation, and mediate bystander suppression ( 3 Metabolic programs governing the Th17/Treg balance Metabolic reprogramming critically controls Th17 and Treg cell fate

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Based on the Certificate of Product Notification issued to the company, any subsequent changes to the information previously submitted to the FDA will render the notification invalid

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doi: 10.1016/j.bmcl.2018.01.018 65

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