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As originally described by Kosower [8], diamide chemically oxidizes the GSH pool without generating ROS during the reaction, which allowed us to alter the antioxidant status without increasing the ROS load directly (as would H 2 O 2 treatment)

Benefits include: Accurate dosing Ease of use Reduced discomfort Improved consistency Dosage Recommendations 6 clicks per dose (250mcg) Approximately 40 doses per pen For best results, use consistently alongside proper recovery strategies

Finally, determination of the IC 50 (Fig

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Two compounds had satisfactory IC 50 values, 5 and 6 , but in addition to these, (1(3bromobenzyl)1 H 1,2,3triazole4,5diyl)dimethanol exhibited an IC 50 of 0.71 M (Figure 5)

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