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The low-energy conformation of the Epitalon peptide was determined, revealing a total charge of 2 at physiological pH 7.0 and an energy value of 294.43 kcal/mol

Its amino acid sequence is Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val, with molecular formula CHNO and molecular weight of approximately 1,419.5 g/mol

The guidance around the management of B12 deficiency in people treated with metformin is a little unclear, owing to a lack of clinical evidence in this area

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