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It detoxifies xenobiotics and heavy metals through a reaction catalyzed by GSH S-transferases that bind them to the sulfhydryl group on the cysteine residue

In contrast, the inactive aMsD4-C6 dimer did not induce detectable phosphorylation events, consistent with the hypothesis that the Met-binding activity of the macrocyclic portions of the dimer are crucial for Met dimerization triggering subsequent phosphorylation of Met as well as the downstream proteins

A peptide designed to interact with amylin receptor systems Unlike naturally occurring amylin, cagrilintide contains specific molecular modifications intended to improve stability and prolong systemic exposure

In Vitro Metabolic Profiling of Weight-Loss-Inducing Amylin Receptor Agonists in the Context of Preventive Doping Research

10.1016/j.clinbiochem.2012.09.009 42 Fernndez-de-Las-PeasC.de-la-Llave-RincnA