This chemogenetic sensor possesses a unique reactivity turn-on mechanism, ensuring that the small molecule is only sensitive to GSH in a desired location
It suggests either multiple pathways activated at different dose ranges or extreme potency with receptor saturation at low doses
Although the biosynthesis of selenocysteine has been characterized as expensive and inefficient, its incorporation into proteins allows biological systems with the ability to execute fundamental chemical functions that are beyond the specialized capabilities of cysteine (263)
G.LatzA.LacombeB.HedrichR.et al
BCCs are significantly more prevalent among Caucasians [50]
[DOI] [PMC free article] [PubMed] [Google Scholar] 70.Leelarungrayub D., Saidee K., Pothongsunun P., Pratanaphon S., Yankai A., Bloomer R.J