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Human CD38 interferes with HIV-1 fusion through a sequence homologous to the V3 loop of the viral envelope glycoprotein gp120

This inhibition causes AICAR to accumulate intracellularly

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Synonyms GSH-PX Sample Type Serum, plasma, cells, cell culture supernatant, tissue Sensitivity 17.17 U Detection Range 17.17-518.32 U Detection Method Colorimetric method Assay type Enzyme Activity Assay time 40 min Precision Average inter-assay CV: 6.200% | Average intra-assay CV: 2.400% Other instruments required Micropipettor, Incubator, Vortex mixer, Centrifuge Other reagents required Normal saline (0.9% NaCl), PBS (0.01 M, pH 7.4) Storage 2-8 Valid period 12 months

In this co-immunoprecipitation assay, we used total protein extracts as a positive control and nave IgG as a negative control

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