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Nat Genet 44(12):13411348 Uva L, Miguel D, Pinheiro C, Antunes J, Cruz D, Ferreira J, Filipe P (2012) Mechanisms of action of topical corticosteroids in psoriasis

Always ensure your prescribing physician is aware of all enzymatic supplements you are taking to prevent unintended pharmacokinetic interactions

Their efficacy depends on the size of the dose, and in practice, administering too low a dose is a common mistake

Glutathione is a natural antioxidant produced by the liver

Ahmad, S., Kumar, V., Ramanand, K

The available findings suggest that silymarin: Can positively influence LDL and VLDL cholesterol levels Significantly increased HDL cholesterol (the so-called "good cholesterol") in studies Can improve oxidative status in the bloodstream Can counteract the reduction of glutathione in the liver caused by a high-cholesterol diet These findings come from clinical studies that were, however, in some cases methodologically heterogeneous