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This dual role suggests that p53 may act as a promising therapeutic target in OA therapy, achieving the synergistic effect of eliminating lesioned cells while protecting normal tissues by precisely regulating the balance between apoptosis and ferroptosis in different cell populations

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Neuromuscular functions can be assessed using electrophysiological methods: measurement of neuromuscular excitability (LABORIT H

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In the absence of Nrf2, ROS production is upregulated, which leads to DNA damage and tumor development