alcohol glutathione depletion and Alcohol: Safeguarding the Liver Glutathione Detox: The Science of

doi: 10.1016/j.biotechadv.2013.06.007, 78 NapoleoniM.KlennerF.KhawajaN.HillierJ

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Glutathione exists in two primary states within the cell: Reduced glutathione (GSH): The active, antioxidant form Oxidized glutathione (GSSG): The spent form, converted back to GSH by the enzyme glutathione reductase using NADPH Under healthy physiological conditions, more than 98% of cellular glutathione exists in the reduced (active) form

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