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A novel prodrug-based strategy to increase effects of bumetanide in epilepsy

Inhibition of the Polyamine Synthesis Pathway Is Synthetically Lethal with Loss of Argininosuccinate Synthase 1

Researchers assume peptide timing is flexible as long as dosing intervals are consistent

Evidence that the L-asparaginase of guinea pig serum is responsible for its antilymphoma effects

In general, PT-141 should not be administered more than twice weekly or eight times monthly, since overly frequent administration can increase the risk of side effects such as skin darkening

This flexibility makes it ideal for various types of patients and protocols