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Data presented are the means of three biological repeats

In the absence of cystine, certain tumor cells can convert methionine to cysteine, enabling them to escape ferroptosis [41]

When in the reduced state, GSH is active and protects cells and DNA by neutralizing reactive oxygen species, such as naturally occurring peroxides and free radicals produced during metabolism that could otherwise damage cellular components

Silymarin can also provide neuroprotection against acrylamide-induced neurotoxicity by reducing oxidative stress and inhibiting cathepsin D activity in the cerebellum of rats 210 (Table 3) 204 , 206, 207, 208, 209, 210

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