Identification of NAPRT inhibitors with anti-cancer properties by in silico drug discovery
[DOI] [PubMed] [Google Scholar] 108.Saleh R.N.M., Hornberger M., Ritchie C.W., Minihane A.M
3IM), as previously observed in mice with myeloid-specific deletion of Gpx4 29
doi: 10.1039/d4fo03671a, 38
Die Natur mute in lebenden Systemen von Anfang an ihre molekularen und Zellstrukturen vor der Einwirkung der zerstrerischen Sauerstoff-Radikale, die durch exogene Noxen und auch im Zellstoffwechsel stndig entstehen, schtzen und entwickelte Schutzenzyme und Schutzmolekle als Scavenger, die diese Radikale sicher und schnell abfangen knnen.Right from the start, nature had to protect its molecular and cell structures in living systems from the effects of the destructive oxygen radicals, which are constantly generated by exogenous noxae and also in cell metabolism, and developed protective enzymes and protective molecules as scavengers that can intercept these radicals safely and quickly
Plant Cell Environ 35(2):454484