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These findings provide direct genetic evidence that variation in the drug target genes contributes to inter-person variability in response and lay the foundation for precision medicine approaches in the treatment of obesity

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After treatment, CRC cells were collected, and chromatin was fragmented using sonication to generate DNA fragments of 200500 bp

During the process of fat metabolism, toxins can be released in the body

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Curr Pharm Anal 13(2):131137 Oubaid EN, Abu-Raghif A, Al-Sudani IM (2023a) Ibudilast ameliorates experimentally induced colitis in rats via down-regulation of proinflammatory cytokines and myeloperoxidase enzyme activity