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PMID: 18694818

Injections can

Effector T cell ferroptosis can result in DAMP release and cell death, which intensifies the inflammatory response

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This initial gradient purification step allows the bead purification to be performed more efficiently

Mitochondria are also crucial for cellular iron metabolism, importing iron via outer membrane voltage-dependent anion channels (VDACs) and inner membrane Mfrn1/2, though mitochondrial iron exporters like CISD1/2 also exist (111, 112)