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As estrogen deficiency-induced redox imbalance may contribute to renal deterioration

Thus, these reports not only reveal a novel ferroptosis surveillance system, the CoQ/FSP-1 system but also solve the long-existing mystery as to why CoQ (CoenzymeQ, ubiquinone), an essential component of the mitochondrial electron transfer chain (ETC), is also located in extramitochondrial spaces where CoQ function was not known (Morr and Morr, 2011)

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A non-interventional control cohort of 20 healthy adults between 20 and 40 years of age was recruited as a reference group

Biochimica et Biophysica Acta (BBA) -