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On the other hand, long-term use of these is also associated with a lot of side effects in the form of electrolyte derangement and bleeding

This is all included in your interpretation of results

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At 6 weeks of age, mice were housed in plastic cages and received standard chow (AIN-76) and water ad libitum prior to experiment maintained on a 12 h/12 h light/dark cycle

TP53, encoded by the TP53 gene and mutated in over 50% of human cancers, is essential for cell-cycle regulation and the induction of programmed cell death

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