FDA banned it in late 2023 "Category 2: Substance with Safety Concerns" Why the FDA banned it: Potential immune reactions (immunogenicity) Manufacturing impurities in compounded versions Complete lack of human safety data Risk of contamination Legal status: NOT FDA-approved Illegal to compound in pharmacies Banned by WADA for athletes Possession not illegal (it's not a DEA scheduled substance) Sold online as "research chemical" 2
Macias, R
Hahn S, Giaglis S, Hoesli I et al (2012) Neutrophil NETs in reproduction: from infertility to preeclampsia and the possibility of fetal loss
Purified Water, Caprylic/Capric Triglyceride, Glycerin, 1,2-Hexanediol, Alpha-Arbutin (2%), Niacinamide (2%), Cetearyl Alcohol, Cetearyl Oliveate, Titanium Dioxide , glutathione (0.15%), hydrolyzed collagen extract, sorbitan olivate, ammonium polyacryloyldimethyltaurate, vinyl dimethicone, glyceryl stearate, polymethylsilsesquioxane, isononylisono Nanoate, t-butyl alcohol, polyhydroxystearic acid, triethoxycaprylylsilane, aluminum hydroxide, ethoxydiglycol, butylene glycol, octyldodecanol, ethylhexylglycerin, Asiaticoside, Hydrogenated Lecithin, Asiatic Acid, Madecassic Acid, Glycolipid, C12-13 Phares-9, Kudzu Root Extract, Giant Pine Leaf Extract, Elm Root Extract, Evening Primrose Extract, Fragrance, Hexylcinnamal , linalool, limonene
PMID 12163549
No trial has established one step-down schedule
