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GSH is the only biologically active form of glutathione in the human body that exerts functions such as antioxidant, detoxification, and immune support

"Purification and characterization of eight glutathione S-transferase isoenzymes of hamster

Few human clinical trials have evaluated the effects of oral GSH supplementation

Glutathione is a natural antioxidant that helps detoxify the body and protect the skin from damage

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The difference between the effects of both QIs on the cell viability ( Figure 2 ) and caspase 3 activation ( Figure 4 ) suggests that upon GSH depletion, the decrease in cell viability is not only apoptosis dependent but also most likely depends other cell death pathways, such as necrosis (Iorga et al., 2017)