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High-dose oral therapy (10002000 micrograms daily) can effectively treat deficiency even in those with impaired intrinsic factor-mediated absorption, relying on passive diffusion

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[2.] It is studied for its involvement in actin binding and cytoskeletal organization as observed in mammalian models

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TB-500, meanwhile, is a synthetic analogue of thymosin beta-4, a ubiquitously expressed 43-amino acid polypeptide involved in cellular differentiation and tissue remodeling