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Given that the role of p53 in senescence regulation is complex, with both promoting and inhibitory effects depending on cell type and stress levels, manipulating the levels of p53 could have unwanted consequences

Your skin may start to sag , making you look older than you actually are

Cheng QY, Zhao JT, Liu S

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(108), who utilized a porcine cartilage bioassay and demonstrated that glucocorticoid treatment in children decreased IGF-I activity

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