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Studies have shown that significant improvements in acne, hyperpigmentation, and fine lines may become apparent after approximately 3 to 6 months of tretinoin therapy (Source: Dermatologic Therapy )

This damaging oxidative stress affects brain health as well, leading to mood disorders like anxiety and depression and even neurodegenerative disease

Investigators tapered or paused doses if intolerance developed (57.4% maintained maximum dose at week 68

Pickart, GHK-Cu has a very high uptake into human skin and is easily absorbed by passing through the lipids of the epidermal barrier

Because the area is numbed with local anesthesia, there is minimal discomfort during the procedure

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