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doi: 10.1021/acs.orglett.6b01324
Dehydroascorbate Reductase (DHAR) Activity To evaluate the DHAR activity, fresh shoot and root material (0.7 g) was placed in a buffered potassium phosphate solution (pH 7.8) comprising 2 mM mercaptoethanol, 1 mM EDTA, and 8% (v/v) glycerin (Nakano and Asada 1981)
1.2 Grxs Grxs were initially identified as alternative electron donors in essential metabolic processes, foremost the reduction of ribonucleotides for DNA synthesis [17,18]
In the context of cerebral ischemia, astrocytes are especially important in regulation and maintenance of glutamate during acute injury, which causes excitotoxicity and perturbates calcium influx resulting in cell death (Brancaccio et al., 2017)
Metformin suppresses lipopolysaccharide (LPS)-induced inflammatory response in murine macrophages via activating transcription factor-3 (ATF-3) induction
Additionally, GSTM1 is a negative regulator of ASK1, a kinase involved in the apoptotic pathway [49]
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