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Quantitatively, the ratio of p-ERK/ERK, p-JNK/JNK and p-p38/p38 were not affected in both Let-7c -low group and Let-7c -over group (Fig

Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy

In ALS, the dysfunctional uptake of glutamate by astrocytic transporters contributes to excitotoxicity at least in a subset of ALS patients [97], however, simple inhibition of glutamate transport failed to produce an ALS-like condition in animals (see section The classical view: microglia as engines of inflammation for more details)

The cosmetic endpoint you're chasing requires sustained dermal exposure over weeks, not peak plasma concentration in the first 90 minutes

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