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For instance, intact cells and cell-free extracts of Bifidobacterium animalis 01 can scavenge hydroxyl radicals and superoxide anion in vitro , whereas in vivo , they increase the antioxidative enzyme activity (225, 226)

Recent research shows that supplementing with the pyridoxine form of B6 at higher doses can paradoxically inhibit the creation of P5P.[ref] Researchers think that excess pyridoxine from high-dose supplements leads to the inhibition of PDXK, the enzyme that converts pyridoxine to P5P