From a molecular viewpoint, key mechanistic themes have emerged: microbial metabolites such as SCFAs, tryptophan metabolites, and bile acids can penetrate into the CNS or signal via the vagus, modulating microglial activation, astrocytic support, and even neuronal gene expression
Furthermore, LS has been proven to have antioxidant properties in a rat model of diabetic nephropathy produced by streptozotocin, as demonstrated by a decrease in renal MDA levels and an increase in renal SOD, catalase, and GSH levels 60
In contrast, under antioxidant/low-ROS conditions (such as in certain tumor microenvironments or after treatment with BPC157 in our study), BACH1 becomes stabilized and can switch to promoting angiogenesis by directly activating target genes like VEGF
Eat Behav
See Glutathione before and after what the research actually shows (honest, research-based, no transformation photos)
The epidemiology, healthcare and societal burden and costs of asthma in the UK and its member nations: analyses of standalone and linked national databases