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Dogs taking the supplement, which provided 225 mg of SAMe and 82 mg of silybin-phosphatidylcholine complex (24 mg of silybin) per day, throughout chemotherapy were less likely to exhibit increased biomarkers of liver damage and were less likely to have their chemotherapy treatments delayed due to increased liver enzyme activity

That distinction matters for understanding what you are working with

Until the system meets patients where they already are in the gray zones between official medicine and survival many of us will keep reconstituting our own solutions, one vial at a time

However, these comparisons are speculative and have not been validated in robust human clinical trials

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Real-world dosing data versus clinical trial protocols Clinical trial dosage schedules represent idealized protocols under controlled conditions