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The microneedles are 200750 microns in length and consist of groups of 150650 microneedles/cm 2 called arrays, having a tip diameter of 25 mm, an interfacial area of 490 mm 2 , with an insertion force required of 0.058 N [171]

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Human skin collagen, mostly Type I, makes up 8090 % of dermal collagen, declining significantly with age due to UV exposure and oxidative stress

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