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Description

PD, Parkinsons Disease

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doi: 10.1038/ncb3064 207 LeonarduzziGScavazzaABiasiFChiarpottoECamandolaSVogelSet al

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Using the CheEA3 transcription factor (TF) enrichment analysis tool, we observed that transcription of 7 ( Ppara, Tgfbr2, Ndrg1, Mt2, Htatip2, Akr1b7, Fbp1 ) of the 9 up-regulated DEGs genes (called group 1 TSGs) could result in TF binding sites (BS) for liver X receptors (LXRs) (GEO-GSE35262, ChIP-Seq)

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Acts through Gq/PLC signaling and intracellular calcium mobilization in receptor-expressing cell models

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