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[21] Handling tobacco and inhaling its dust is an occupational hazard for beedi workers, as an increased level of chromosome aberrations was found in a scientific study

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DiFranza JR, Savageau JA, Fletcher K, et al

This leads to a long-lasting cough and inflamed airways

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This transition suggests that prolonged exposure within a three-dimensional epithelial context recapitulates mutational processes characteristic of smoking-related lung cancers, emphasizing that the tissue-level environment facilitates the emergence of canonical tobacco-associated genomic patterns