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We think that while it is clear that different endpoints may yield quite different results, the human MOE for cannabis based on the endpoint psychotropic effects can be seen as general validation of the MOE concept, because the resulting values below 1 are expected as the psychotropic effect is the desired endpoint (and hence the psychotropic threshold dose is exceeded by drug users)

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DNA adducts are central to the carcinogenic process as induced by tobacco products

Managing Stings: Mask the Alarm If you are stung, that bee releases a strong alarm pheromone on your suit or skin

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Nickel induces inflammatory activation via NF-B, MAPKs, IRF3 and NLRP3 inflammasome signaling pathways in macrophages