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Nicotine Strength: Higher nicotine concentrations can reduce the number of puffs needed to satisfy cravings

Sixth, although some studies have begun to characterize the impact of smoking on gray matter in young adult/adolescent smokers [85, 86], the concurrent influence of marijuana [111] or alcohol use [112], and sex differences among smokers [17], as more studies accumulate regarding the influence of these and other important factors on gray matter alterations, it will become possible to better characterize the specificity of the meta-analytic effects identified herein

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