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Smoking constitutes the leading cause of avoidable illness, disability, and death in the US

The Cochrane Review's study, a so-called meta-analysis, drew on two randomized trials covering 662 smokers, and also considered evidence from 11 observational studies, to examine the effects of e-cigarettes on quit rates and on helping people cut down their cigarette smoking by at least half

Accessed 13 July 2021 Acknowledgements Funding No funding or sponsorship was received for this study or publication of this article

Vaping among middle-and high-school students has seen an exponential increase between 2017 and 2019, leading to the highest number of 5 million users in the year 2019 [16], [17]

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