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In COVID-19 patients, M2 macrophages dominate M1 types in BAL samples of cases, indicating their crucial involvement in inflammation and fibrogenesis [53]

Smokers and COPD patients, who suffer from weight loss, are less prone to obesity, and smoking cessation is associated with weight gain in active smokers [241, 242]

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It does mean that COVID-19 has a lot more trouble accessing the ACE2 receptor to gain entry, but in the same vein, increased mucosal volume gives more places for COVID particles - or other viruses - to get a foothold

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Jay Lehr, science director at the right-wing Heartland Institute, concurs