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Finally, the Japanese experience points to the potential to achieve dramatic reductions in smoking without the planning or approval of government regulators

Biochimica et Biophysica Acta (BBA) - Enzymology

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At the same time, they released results from a study published in the New England Journal of Medicine that modeled what would happen after implementing a policy lowering nicotine levels in cigarettes and other combustible tobacco products, including roll-your-own tobacco, pipe tobacco, and non-premium cigars