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It is a preventable cause of disease and ultimately death

Clinical cross-sectional studies demonstrated that urinary excretion of proximal tubular enzymes (beta-hexaminidase, N -acetyl-beta-d-glucosaminidase, neutral endopeptidase), and free filtered beta-2 microglobulin and retinol binding protein was higher in smoking individuals than in their nonsmoking counterparts [24,25,26,27]

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But unlike patches or gums, e-smokes operate in a legal gray area