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Too much heat could destroy the flavor of your nicotine, especially if you're using snus

At this weeks Smokefree Oceania conference in Auckland, New Zealand, Penelope Truman of the Institute of Environmental Science and Research (ESR) presented a study that showed how rats exhibited a greater willingness to obtain a dose of smoke from non-nicotinic rolling tobacco compared with doses of nicotine and smoke from factory-made cigarettes that contain nicotine

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However, in both cases, staining was intracellular suggesting a non-specific uptake mechanism of the IgG antibody possibly due to presence of Fc receptors on NHBE cells

PMID 26060112