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The base is a Virginia soft cut at 5MG, calibrated specifically so the tobacco doesnt fight the capsule chemistry

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However, various in vitro experiments revealed CSC-induced cellular atherogenic alterations in endothelial cells as for instance: (a) genotoxic effects, 35 (b) alteration in the cytokine expression, 36 (c) upregulation of genes involved in matrix degradation, 37 (d) CSC-induced adherence of monocytes to the endothelial cell monolayer, 38 (e) CSC-induced surface expression of adhesion molecules on endothelial cells and transendothelial migration of monocytes 39 and (f) decreased migration ability of endothelial cells in vitro

Tossing it onto grass, mulch, leaves, or even pavement can cause burns, damage, or in extreme cases, start a fire