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Family Smoking Prevention and Tobacco Control Act (FSPTCA) embraces the concept of THR and defines a modified risk tobacco product (MRTP) as any tobacco product that is sold or distributed for use to reduce harm or the risk of tobacco-related disease associated with commercially marketed tobacco products [8]

However, factors like puff frequency, device type, and user habits affect the actual amount of nicotine absorbed

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tobacco and moist smokeless tobacco products

Spending a fair bit of time indoors

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