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The 5 stages of tobacco addiction are as follows: Pre-contemplation: In this initial stage, individuals do not recognize their tobacco use as a problem

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Neck: Maple neck with white side-dots

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Nicotine is known to bind to nAChRs in the brain and alter neurotransmitter transmission 44,45

The associations of smoking with depression, schizophrenia 41 , suicide ideation 42 and bipolar disorder 36 have been revealed in previous MR studies