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Zhu W, Friedman H, Klein TW

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Although all studies consistently indicated a statistically significant link between e-cigarette use and the odds of having COPD, the selected studies exhibited high heterogeneity ( I 2 = 98.85%), and the prediction interval for the ORs was 0.84 to 4.92 (Figure 2A)

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Moreover, as e-cigarettes and vapor products are tobacco harm reduction tools, lawmakers should avoid taxing such products as it may deter current smokers from switching to a safer alternative