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Data availability All data not included in the paper itself is available upon reasonable request from the corresponding author

On top of that, it may also be a viable source of defense against systemic inflammation, which could be applicable to multiple forms of pain

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10.1002/cmdc.201700781 32 ChenZ.LiuX.-A.KennyP

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The concept of using pipe tobacco in cigars was quite revolutionary thinking at the time but it proved successful because by 1996, Black and Mild cigars were the top selling brand in the Middleton family, a streak it has maintained for decades