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Fire fighters with repeated acute exposure to fire smoke have a decreased life expectancy by about 10 years

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The calculated area under the curve for cotinine N-oxide concentrationtime and MRT in the case of the studied animal groups amounted to from 5.46 1.41 ng/mL/h to 24.51 11.18 ng/mL/h for AUC, and from 3.24 0.45 h to 4.58 1.65 h for MRT, but these differences were not statistically significant (Table 3)