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This aberrant immune response is characterized by airway eosinophilia, goblet cell hyperplasia, airway wall remodeling, and production of allergen-specific IgE, all driven by T helper (Th)2-derived cytokines, such as interleukin (IL)-4, IL-5, and IL-13

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Early-onset alcohol, tobacco, and illicit drug use with age at onset of hypertension: a survival analysis Kesheng Wang, Saima Shafique, Nianyang Wang, Suzy Walter, Xin Xie, Ubolrat Piamjariyakul, Erin Winstanley Social Psychiatry and Psychiatric Epidemiology 4