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Male and female rats exposed to high doses of smoke from nonmentholated cigarettes also had a significant increase in cardiomegaly (high ratio of heart weight to body weight)

Nearly 100,000 Californian smokers were studied, and the conclusions were shocking, even to oncologists

Snus was not banned in the USA, but according to the Swedish Match representative at the GFN Conference, when the company wanted to introduce a modified risk product they had to submit a research evidence report which ran to 140,000 pages

1 , 2 Additionally, non-smokers, including children, report high awareness of warning labels

Packaging for nicotine pouches must provide a health warning, plain packaging is not required, but packaging may not appeal to minors