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It may be something as simple as an over-the-counter decongestant or even a surgical procedure to remove obstructions that are the culprit

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Nehls, Littered cigarette butts as a source of nicotine in urban waters

For some smokers, the ritual of having a cigarette can psychologically signal the body to prepare for a bowel movement, especially if they have associated smoking with bathroom breaks over time

That is a target where these safe cigarettes may work well. Smokers are already complaining that the new cigarettes go out too easily