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It is possible that the hyperinflation seen in cannabis users in addition to the Valsalva maneuver often used with inhalation may be involved in the cases of spontaneous pneumothorax and/or pneumomediastinum and of the peripheral apical lung bullae [50] that have been reported in isolated cases of marijuana smokers

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[3] The American version of Joe Camel was created later by art designer Mike Salisbury working on contract for the brand's main agency, McCann-Erickson New York