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Topography data is not presented in this manuscript and a thorough description of the emotions and activities reported using EMA during each cigarette session has been published [18]

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Exercise leads to increased HIF-1 levels due to increased muscle oxygen consumption, and preclinical studies suggest HIF-1 is essential for the exercise-induced anti-apoptotic effects in neurons, but this is not investigated in experimental PD models specifically 92,93,94

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