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Additionally, biomarker-based evidence of cancer risk can be easily investigated through rigorously designed randomized controlled trials to assess short-to-medium-term exposure effects

Anti-smoking groups also point to Big Tobaccos history of manipulating public opinion and government efforts against smoking: In 2006, a federal judge ruled that Big Tobacco had lied and deceived the American public about the effects of smoking for more than 50 years

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Approximately 14 percent of U.S